Comparing serologic response against enteric pathogens with reported diarrhea to assess the impact of improved household drinking water quality

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Journal: Am J Trop Med Hyg 2007/07/11
Published: 2007
Authors: Crump, J. A.;Mendoza, C. E.;Priest, J. W.;Glass, R. I.;Monroe, S. S.;Dauphin, L. A.;Bibb, W. F.;Lopez, M. B.;Alvarez, M.;Mintz, E. D.;Luby, S. P.
Address: Foodborne and Diarrheal Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. jcrump@cdc.gov

We evaluated enteric infection serology as an alternative outcome measure to diarrhea prevalence in a randomized controlled trial of household-based drinking water treatment; 492 households were randomly assigned to 5 household-based water treatment interventions or control. Individuals were followed weekly over 52 weeks to measure diarrhea prevalence. Study subjects of age

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